91糖心vlog传媒

教育及工作经历：

2020- 至今91糖心vlog传媒博士生导师、教授（2022年起任生命科学学院科研副院长）

2017-2019 91糖心vlog传媒特聘研究员

2014-2016 北大-耶鲁联合中心进行博士后

2012-2014 耶鲁大学，联合培养博士生

2010-2012 加州大学伯克利分校，联合培养博士生

2009-2014 北京大学，生命科学学院，理学博士

2005-2009 北京大学，生命科学学院，理学学士

研究领域：

致力于研究环境因子调控植物种子萌发和幼苗形态建成的分子机制，重点关注光温信号对植物生长发育的分子调控机制，系列成果发表在Cell、PNAS、Developmental Cell、Current Biology和Plant Cell等国际着名期刊上。

代表性成果：

第一或通讯（含共同）：

1.Gao, L.;Xu, S.;Zhang, J.;Kang, J.; Zhong, S.; Shi, H.*Promotion of seedling germination in Arabidopsis by B-box zinc finger protein BBX32, Current Biology 2024,in press.

2. Zhao, Y.#; Shi, H.#; Pan, Y.#; Lyu, M.; Yang, Z. X.; Kou, X. X.; Deng, X. W.; Zhong, S. W.*, Sensory circuitry controls cytosolic calcium-mediated phytochrome B phototransduction. Cell 2023,186 (6), 1230-1243.

3. Shi, H.*; Zhong, S. W.*, Light and temperature perceptions go through a phase separation. Current Opinion in Plant Biology 2023,74, 102397.

4. Wu, Q.; Zhong, S.; Shi, H.*, MicroProtein: Dynamic and accurate regulation of protein activity. J Integr Plant Biol 2022, 64,812-820.

5. Lyu, M.#; Shi, H.#; Li, Y.; Kuang, K.; Yang, Z.; Li, J.; Chen, D.; Kou, X.; Zhong, S.*, Oligomerization and photo-deoligomerization of HOOKLESS1 controls plant differential cell growth. Dev Cell 2019,51 (1), 78-88.

6. Shi, H.#; Lyu, M.#; Luo, Y.#; Liu, S.#; Li, Y.; He, H.; Wei, N.; Deng, X. W.*; Zhong, S.*, Genome-wide regulation of light-controlled seedling morphogenesis by three families of transcription factors. Proc Natl Acad Sci U S A 2018,115 (25), 6482-6487.

7. Luo, Y.; Shi, H.*, Direct regulation of phytohormone actions by photoreceptors. Trends Plant Sci 2018, 24,105-108.

8. Pan, Y.; Shi, H.*, Stabilizing the transcription factors by E3 ligase COP1. Trends Plant Sci 2017, 22,999-1001.

9. Liu, X.; Liu, R.; Li, Y.; Shen, X.; Zhong, S.*; Shi, H.*, EIN3 and PIF3 form an interdependent module that represses chloroplast development in buried seedlings. Plant Cell 2017,29 (12), 3051-3067.

10. Shi, H.#; Shen, X.#; Liu, R.; Xue, C.; Wei, N.; Deng, X. W.*; Zhong, S.*, The red light receptor phytochrome B directly enhances substrate-E3 ligase interactions to attenuate ethylene responses. Dev Cell 2016,39 (5), 597-610.

11. Shi, H.; Liu, R.; Xue, C.; Shen, X.; Wei, N.; Deng, X. W.*; Zhong, S.*, Seedlings transduce the depth and mechanical pressure of covering soil using COP1 and ethylene to regulate EBF1/EBF2 for soil emergence. Curr Biol 2016,26 (2), 139-149.

12. Shi, H.#; Wang, X.#; Mo, X.; Tang, C.; Zhong, S.*; Deng, X. W.*, Arabidopsis DET1 degrades HFR1 but stabilizes PIF1 to precisely regulate seed germination. Proc Natl Acad Sci U S A 2015,112 (12), 3817-3822.

13. Shi, H.#; Zhong, S. W.#; Mo, X. R.#; Liu, N.; Nezames, C. D.; Deng, X. W.*, HFR1 sequesters PIF1 to govern the transcriptional network underlying light-initiated seed germination in Arabidopsis. Plant Cell 2013,25 (10), 3770-3784.

14. Zhong, S. W.; Shi, H.#; Xue, C.; Wang, L.; Xi, Y. P.; Li, J. G.; Quail, P. H.; Deng, X. W.*; Guo, H. W.*, A molecular framework of light-controlled phytohormone action in Arabidopsis. Curr Biol 2012,22 (16), 1530-1535.

合作作者：

15. Chen, D.#; Lyu, M.#; Kou, X.; Li, J.; Yang, Z.; Gao, L.; Li, Y.; Fan, L. M.; Shi, H.; Zhong, S.*, Integration of light and temperature sensing by liquid-liquid phase separation of phytochrome B. Mol Cell 2022, 82(16):3015-3029.

16. Wu, Q.; Li, Y.; Lyu, M.; Luo, Y.; Shi, H.; Zhong, S.*, Touch-induced seedling morphological changes are determined by ethylene-regulated pectin degradation. Sci Adv 2020,6 (48).

17. Wu, Q.; Kuang, K.; Lyu, M.; Zhao, Y.; Li, Y.; Li, J.; Pan, Y.; Shi, H.; Zhong, S.*, Allosteric deactivation of PIFs and EIN3 by microproteins in light control of plant development. Proc Natl Acad Sci U S A 2020,117 (31), 18858-18868.

18. Yu, Y.; Wang, J.; Shi, H.; Gu, J.; Dong, J.; Deng, X. W.; Huang, R.*, Salt stress and ethylene antagonistically regulate nucleocytoplasmic partitioning of COP1 to control seed germination. Plant Physiol 2016, 170 (4):2340-2350.

19. Zhong, S. W.; Shi, H.; Xue, C.; Wei, N.; Guo, H. W.*; Deng, X. W.*, Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth. P Natl Acad Sci USA 2014,111 (11), 3913-3920.

20. Pfeiffer, A.; Shi, H.; Tepperman, J. M.; Zhang, Y.; Quail, P. H.*, Combinatorial complexity in a transcriptionally centered signaling hub in Arabidopsis. Mol Plant 2014,7 (11), 1598-1618.

21. Peng, J. Y.; Li, Z. H.; Wen, X.; Li, W. Y.; Shi, H.; Yang, L. S.; Zhu, H. Q.; Guo, H. W.*, Salt-Induced stabilization of EIN3/EIL1 confers salinity tolerance by deterring ROS accumulation in Arabidopsis. Plos Genet 2014,10 (10).

22.Zhang, Y.; Mayba, O.; Pfeiffer, A.; Shi, H.; Tepperman, J. M.; Speed, T. P.; Quail, P. H.*, A quartet of PIF bHLH factors provides a transcriptionally centered signaling hub that regulates seedling morphogenesis through differential expression-patterning of shared target genes in Arabidopsis. Plos Genet 2013,9 (1).

23. Zhong, S.; Zhao, M.; Shi, T.; Shi, H.; An, F.; Zhao, Q.; Guo, H.*, EIN3/EIL1 cooperate with PIF1 to prevent photo-oxidation and to promote greening of Arabidopsis seedlings. Proc Natl Acad Sci U S A 2009,106 (50), 21431-21436.

学术任职：

中国植物学会植物生理及分子生物学专业委员会委员，中国细胞生物学会植物细胞生物学分会委员，《植物生理学报》编委，91糖心vlog传媒校学术委员会青年委员，生命科学学院学术委员会委员

获奖情况：

2023 北京高校优秀共产党员及北京市巾帼科技领航导师

2022 北京市第十叁次党代会代表

2021 “首都最美巾帼奋斗者”称号

执教课程：

《植物学》本科专业必修课