Title：Current understanding of BIK1 in immune signaling

Speaker: Jian-Min Zhou (周俭民)

罢颈尘别：4月12日下午2:00

搁辞辞尘：理科楼430

础产蝉迟谤补肠迟：

Plant cell surface-localized immune receptors, designated pattern-recognition receptors, perceive molecular patters associated with pathogenesis to activate defenses. BIK1 and closely related cytoplasmic kinases play a central role in pattern-triggered immunity. These kinases directly associate with diverse pattern-recognition receptors to relay immune signals. Over the past eight years, tremendous progress has been made concerning how these kinases are regulated at the levels of phosphorylation and protein stability. We have also learned how these kinases regulate downstream signaling to activate defenses. The study of BIK1 and related kinases not only advances our understanding of innate immunity, but also brings new insight in transmembrane signaling in general. 

报告人介绍:

中国科学院遗传与发育研究所研究员

曾任:美国堪萨斯大学副教授(终身教职)、北京生命科学研究所高级、资深研究员

国家自然科学基金委创新团队首席科学家

Board of Directors, International Society of Molecular Plant-Microbe Interactions

Review Editor, eLife

Senior Editor, Current Protocols in Plant Biology

Section Editor, PLoS Pathogens

Editor，Molecular Plant

在Nature, Science, PNAS, Cell Host & Microbe, eLife, Plant Cell, EMBO J, Current Biology等刊物发表多篇论文,并应邀在Cell Host & Microbe, Plant Cell, EMBO J, Current Biology, Current Opinion in Plant Biology等刊物撰写综述和评述.