报告题目：Mitochondrial contact sites and lipid homeostasis -what we can learn from yeast

报告人：Dr. Kai Stefan Dimmer

德国图宾根大学生物化学研究所

时间：2019年4月4日下午2:00

地点：理科楼430

报告内容介绍:

Mitochondria are unique organelles since two distinct membranes surround them, the mitochondrial inner and outer membrane. They are not participating in membrane vesicle trafficking. Yet, mitochondria only comprise a subset of metabolic pathways for the synthesis of membrane lipids, therefore most species and precursors have to be imported at membrane contact sites as e.g. the ER mitochondria encounter structure (ERMES). Moreover, since both membranes are separated from each other by the intermembrane space, lipids also have to be shuttled across this hydrophilic compartment. Most of the processes that contribute to mitochondrial lipid homeostasis at so-called membrane contact sites as well as inside mitochondria themselves are only at the beginning of being understood.